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Medical Office Space in Tyler, East Texas and Dallas-Fort Worth

Scarborough Commercial Real Estate helps physicians, dental and specialty practices, hospital-affiliated groups and healthcare investors lease, buy and sell medical office space in Tyler, Texas and the surrounding East Texas markets. Led by Sam Scarborough, CCIM, we know the buildings around Tyler's hospitals and medical district, which landlords build out clinical space, and what the market actually signs for.

Why Medical Real Estate Matters in Tyler

Healthcare is Tyler's dominant industry. According to UT Tyler's Hibbs Institute, it accounts for 17.5 percent of the local economy, more than oil and gas, manufacturing or retail, and CHRISTUS Trinity Mother Frances and UT Health East Texas together employ nearly 9,000 people. The $308 million UT Tyler School of Medicine building in the Midtown District, connected by skybridge to UT Health East Texas, is the most significant single real estate investment in the region in recent memory. Each graduating doctor who stays in East Texas becomes a tenant, an employer and a catalyst for the medical office development that follows healthcare access. Read more in our column How Medical Real Estate Became Tyler's Most Important Economic Asset.

Who We Help

Practices and providers: physicians, dentists, orthodontists, dermatology, physical therapy, urgent care, imaging, behavioral health and specialty groups opening a first office, adding a location or relocating closer to the hospitals.

Landlords and investors: owners of medical office buildings and medical-adjacent retail who need qualified healthcare tenants, and investors who want to buy medical properties with durable, long-term tenants.

Where Medical Space Is in Tyler

Most medical office space sits in the medical district around CHRISTUS Trinity Mother Frances and UT Health East Texas in the Midtown area, along South Broadway and the South Loop 323 corridor, and in newer medical-adjacent retail centers on the south side. Hospital-adjacent buildings fill fastest; well-located space near the hospitals rarely stays available long.

How a Medical Office Search Works With Us

We start with your specialty, patient volume, parking, exam room count, timing and budget.

We pull every space that fits, including second-generation medical space with plumbing and build-out already in place, and off-market opportunities.

We tour the shortlist and give you a frank read on build-out cost, parking and visibility.

We negotiate the letter of intent and the lease or purchase contract, including tenant improvement allowance, exclusives and renewal options, and stay involved through build-out and opening.

In most tenant representation deals the landlord pays our fee, so there is no cost to the practice for our representation.

Current Listings

Browse our current office availability or call us for medical space not yet on the market.

View Space for Lease View Property for Sale

What Clients Say

Scarborough Commercial Real Estate is rated 5.0 on Google by East Texas clients.

Frequently Asked Questions

Where is the Tyler medical district?

Tyler's medical district is centered on CHRISTUS Trinity Mother Frances and UT Health East Texas in the Midtown area, with medical office buildings clustered around both hospitals and along South Broadway and Loop 323.

What does medical office space cost to lease in Tyler?

Medical space generally leases above general office because of the plumbing, HVAC and build-out it requires, and hospital-adjacent buildings command the most. The practical number depends on whether the space is already built out for clinical use. Call us for current asking rents on specific buildings.

Do you represent doctors and practices?

Yes. Tenant representation for practices is a core part of our work, from a first office to a multi-location group, and the landlord usually pays our fee.

Can you find space near CHRISTUS or UT Health?

Yes. We track availability in the buildings around both hospitals, including spaces that come open before they are publicly listed.

Do you handle medical office sales?

Yes. We represent sellers and buyers of medical office buildings and condominiums, and investors buying medical properties for the long-term tenants they carry.

Talk to a Medical Office Broker

Call (903) 707-8560 or send us a note about your practice's space. 410 W. Erwin, Tyler, TX 75702.